Get BookIL-17 IL-22 and Their Producing Cells Role in Inflammation and Autoimmunity (Progress in Inflammation Research)

[Download Ebook.kfOc] IL-17 IL-22 and Their Producing Cells Role in Inflammation and Autoimmunity (Progress in Inflammation Research)

[Download Ebook.kfOc] IL-17 IL-22 and Their Producing Cells Role in Inflammation and Autoimmunity (Progress in Inflammation Research)

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Book Details :
Published on: 2012-12-13
Released on: 2012-12-13
Original language:

The knowledge of Th17 cells and other cell populations which secrete IL-17A, and/or IL-22 has expanded tremendously since the publication of the first edition “Th17 Cells: Role in Inflammation and Autoimmune Disease” in 2008. The present volume has been completely revised with the addition of new chapters on the IL-17 receptor family and signaling, and an in-depth review of IL-22 and innate lymphoid cells. The differentiation of naïve T cells into regulatory T cells and Th17 cells as well as the plasticity of Th17 cells is discussed. The role of IL-22 in cutaneous inflammation including psoriasis has been reviewed. In addition, the volume contains critical updates on autoimmunity, organ transplantation, tumor immunology and genetic mouse models for mechanistic studies. Lastly, the latest clinical progress in neutralizing antibodies to IL-17A, IL-17RA not only confirms the therapeutic promise foreseen in 2008, but also improves our knowledge of the pathogenesis of autoimmune diseases. In summary, this is a timely update and important review of the clinical and experimental aspects of IL-17, IL-22 and their producing cells. Psoriasis NEJM Immunopathologic Features of Psoriasis. Studies in the 1970s showed the presence of substantial numbers of immune cells in patients with psoriasis suggesting a ... The Pathogenesis of Rheumatoid Arthritis NEJM Activation of the Innate Immune System. A variety of innate effector cells including macrophages mast cells and natural killer cells are found in the synovial ... Cytokines in the pathogenesis of rheumatoid arthritis ... Top of page Abstract. Cytokines regulate a broad range of inflammatory processes that are implicated in the pathogenesis of rheumatoid arthritis. In rheumatoid joints ... Role of the Microbiota in Immunity and Inflammation The microbiota plays a fundamental role on the induction training and function of the host immune system. In return the immune system has largely evolved as a ... How functional foods play critical roles in human health Abstract. How do functional foods affect human health? To answer this question it is important to understand what happens when food is digested and taken up by the ... The IL-23-IL-17 immune axis: from mechanisms to ... Interleukin-17 (IL-17) signalling is activated upon binding of IL-17 to a dimeric receptor complex that is composed of IL-17 receptor A (IL-17RA) and IL-17RC. Graves' Disease and the Manifestations of Thyrotoxicosis ... ABSTRACT. Graves disease includes thyrotoxicosis goiter exophthalmos and pretibial myxedema when fully expressed but can occur with one or more of these features.
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